Herb, Nutrient, and Drug Interactions

Herb, Nutrient, and Drug Interactions: Clinical Implications and Therapeutic Strategies, 1e Paperback – December 20, 2007

Author: Mitchell Bebel Stargrove ND LAc | Language: English | ISBN: 0323029647 | Format: PDF, EPUB

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Herb, Nutrient, and Drug Interactions: Clinical Implications and Therapeutic Strategies, 1e – December 20, 2007
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"This is certainly one of the best books around to discuss the complex area of interactions”
Complementary Medicine, March / April 2009

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Paperback: 960 pages
Publisher: Mosby (December 20, 2007)
Language: English
ISBN-10: 0323029647
ISBN-13: 978-0323029643
Product Dimensions: 10.6 x 8.7 x 1.2 inches
Shipping Weight: 4.4 pounds (View shipping rates and policies)
Amazon Best Sellers Rank: #736,686 in Books (See Top 100 in Books)

I have been looking for a book like this for years. It not only discusses the methods by which herbs or supplements and drugs interact, it comprehensively discusses the way that supplements perform in the body. The 932 page, double columned book deals primarily with supplements (there are only 30 herbs), with detailed discussion of the substance including pharmacokinetics, pharmacogenomics and pharmacogenetics, interactions between them and how to manage the interactions.

For instance, the Vitamin K section is 10 pages long, packed with information on the nutrient (chemistry and forms, physiology and function,) the nutrient in clinical function (possible uses, deficiency symptoms including a discussion of the functional sources of reference intakes and controversies thereof, nutrient preparations available, dosage forms available, dosage ranges for various classes of patients, lab values), safety profile (adverse effects, specific populations at risk including pregnancy and nursing, infants and children, contraindications), an interactions review (Strategic considerations which provides excellent information on not only coagulation but also fibrinolysis and the use of probiotic therapy in its administration, and anti-coagulent overdose). The Nutrient-drug interactions section is over 8 pages long, discussing antibiotics and systemic antimicrobial agents by name with interaction types and significance, effect and mechanism of action, research, reports, nutritional therapeutics, clinical concerns and adaptations. And then repeats this information for bile acid sequestrants, corticosteroids, mineral oil, anticonvulsants and blood thinners.

Since the late 1990s, when conventional medicine discovered the magnitude of the public use of herbs and supplements, a series of books on herbal safety, including drug-herb interactions, has appeared. This body of literature has been seriously flawed. Most of the authors were not themselves clinicians experienced with the traditional or contemporary literature on the agents being discussed and were equally unfamiliar with their actual clinical or commercial use of the items. Several texts written by alternative practitioners or herbalists either completely avoided the topic of drug-herb interactions, or tended to understate safety concerns. And ultimately, all these books failed to comprehensively evaluate the evidence for interactions or accurately distinguish between purely theoretical concerns and those based on clinical evidence.
Herb, Nutrient, and Drug Interactions corrects each of these problems, and is the first complete text on the subject, its predecessors being false starts or partial contributions in the field. The authors are all experienced practitioners. Stargrove is a licensed naturopathic physician and acupuncturist; Treasure is a professional herbalist, and McKee is a medical doctor board certified in integrative medicine and also certified in clinical nutrition. A board of 18 interdisciplinary reviewers, the great majority of them clinicians, adds further depth of practical and scholarly expertise.
The authors offer 1-3 page monographs on 70 therapeutic agents, including 30 herbs, 12 vitamins, 9 minerals, 6 amino acids, and 13 neutraceuticals. The monographs are extensive, and most are accompanies by summaries, so the book may be used for in-depth study or for quick reference.