Friday, December 27, 2013

Blockbuster Drugs


Blockbuster Drugs: The Rise and Decline of the Pharmaceutical Industry Hardcover – January 2, 2014

Author: Visit Amazon's Jie Jack Li Page | Language: English | ISBN: 0199737681 | Format: PDF, EPUB

Blockbuster Drugs: The Rise and Decline of the Pharmaceutical Industry – January 2, 2014
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From Publishers Weekly

Li (Laughing Gas, Viagra and Lipitor: The Human Stories Behind the Drugs We Use) surveys Big Pharma's €œgolden age€ with a nostalgic yet thoughtful history of the science and personalities behind drugs that changed the lives of countless patients while making billions of dollars for the companies that brought them to market. The author examines five classes of blockbusters that gave Big Pharma both esteem and fortunes: from Tagament and Prilosec for peptic ulcers to blockbuster allergy treatments such as Benadryl and Claritin, to blood thinners that refined old-line heparin, to the modern conquest of pain with drugs descended from opium—€œone of the first medicines for man.€ Li also engagingly relates the tales of the human conflict often involved with discovery, like a precipitous one-year drop in profits that resulted from a feud between an American drug company and one of its Canadian counterparts. Drug discovery is now getting more attention from academia as new products wane, Li notes, but he decries Big Pharma's €œmerger mania€ and its tarnished reputation, especially following Merck's abrupt withdrawal of anti-inflammatory Vioxx because it led to increased risk of heart attacks and strokes among those taking it. Nevertheless, Li delights in the €œcreativity, serendipity and perseverance€ of big drug discoveries—lessons he hopes may prompt a renaissance in the industry. (Dec.)

Review


"Once again, with his latest book, Jack Li has produced a wonderfully fascinating and rich history of the so-called 'Blockbuster Drugs.' From the treatment of ulcers and acid reflux, to the control of allergies, and the conquest of pain, Dr. Li weaves a beautiful tale of these extraordinary medicines, familiar to all. The book is full of detail, with an extensive bibliography, and, for the molecular connoisseur, includes chemical structures in the Appendix. Dr. Li is rapidly becoming a premiere figure for writing about medicines for the educated population!" -- Gordon W. Gribble, The Dartmouth Professor of Chemistry, Dartmouth University


"This enjoyable book describes more than a century of progress in the development of many major new medicines for the treatment of human illness. It provides deep insights into the process of innovation and also the remarkable individuals responsible for it. The accounts are understandable to the non-scientist but also valuable to researchers and practitioners of modern medicine. There is a nice balance between the human, historical and medical sides of drug discovery -- one of the most consequential activities of our times." -- E.J. Corey, Nobel Laureate, Harvard University


"Jie Jack Li takes us through the ages of pharmaceuticals in this informative and engaging book. Professor Li links the medical world with its much broader cultural background in a way that will appeal to many. If you are interested in the past, present, and future of the medicines you take and the background to their production, look no further than this book." --New York Journal of Books


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Direct download links available for Blockbuster Drugs: The Rise and Decline of the Pharmaceutical Industry – January 2, 2014
  • Hardcover: 240 pages
  • Publisher: Oxford University Press (January 2, 2014)
  • Language: English
  • ISBN-10: 0199737681
  • ISBN-13: 978-0199737680
  • Product Dimensions: 8.3 x 5.7 x 0.8 inches
  • Shipping Weight: 1 pounds (View shipping rates and policies)
  • Amazon Best Sellers Rank: #378,539 in Books (See Top 100 in Books)

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