Sunday, July 28, 2013

Stahl's Essential Psychopharmacology


Stahl's Essential Psychopharmacology: Neuroscientific Basis and Practical Applications (Essential Psychopharmacology Series) Paperback – Bargain Price, March 17, 2008

Author: Visit Amazon's Stephen M. Stahl Page | Language: English | ISBN: B00D57FC4E | Format: PDF, EPUB

Stahl's Essential Psychopharmacology: Neuroscientific Basis and Practical Applications – Bargain Price, March 17, 2008
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Review

"Dr. Stahl's latest edition remains the clearest book covering all the latest advances and developments in psychopharmacology. The method of teaching through illustration and conceptual form should continue to make it very popular.....Completely revised and updated with the latest developments, this editioncaptures the shift from the receptor model to brain circuits and signal transduction cascades. The basic sciences section has been doubled to cover the advances in the understanding of the functioning of neurons, signal transduction cascades, ion channels, genetics, brain circuits, imaging, and disease models of pathophysiology. The clinical section has been expanded from the previous edition to discuss the psychiatric disorder and the corresponding malfunctioning brain circuit. This section also details the advances in the latest hypothesis of the disorder as well as the latest drugs related to the treatment of the disorder. New to this edition is a chapter on pain and the treatment of fibromyalgia and other somatic syndromes. Separate chapters now cover dementia and attention deficit disorders with the newest treatments as well as drugs that are in the pipeline. Of special note is the chapter on reward that has been expanded from substance abuse to cover disorders of sexual function, eating, and impulsivity. Unique to Dr. Stahl's books are the illustrations, which have been expanded in this edition to reflect the latest advances. Information is presented in conceptual form that makes it easier to read and understand. The book maintains a consistent format and is augmented with more graphs and tables."
--Doody's Book Review Service

"Stephen Stahl is one of the most recognizable names in psychopharmacology. He is an inspiring teacher who has a knack for synthesizing complex scientific information for students, residents, psychiatrists, and nonmedical mental health practitioners....[H]e has started publishing psychopharmacology books that are not only very readable and up-to-date, but are in my opinion the most creatively illustrated texts of psychopharmacology. My trainees rave about his books and quote them often."
--Journal of Clinical Psychiatry

Book Description

This expanded and fully revised edition explains and illustrates the neurobiological concepts underlying the drug treatment of psychiatric disorders. For the student it provides an easily readable and highly illustrated introduction to the subject. For the physician or scientist it offers a quick review of psychopharmacology and the drug treatment of mental illness.
See all Editorial Reviews

Direct download links available for Stahl's Essential Psychopharmacology: Neuroscientific Basis and Practical Applications (Essential Psychopharmacology Series) Paperback – Bargain Price, March 17, 2008
  • Series: Essential Psychopharmacology Series
  • Paperback: 1132 pages
  • Publisher: Cambridge University Press; 3 edition (March 17, 2008)
  • Language: English
  • ISBN-10: 0521746094
  • ASIN: B00D57FC4E
  • Product Dimensions: 9.7 x 6.8 x 2 inches
  • Shipping Weight: 4.9 pounds (View shipping rates and policies)
  • Amazon Best Sellers Rank: #1,476,122 in Books (See Top 100 in Books)
The biochemical illustrations are excellent but the text is lacking in nuance. (Maybe that book would require another thousand pages.) The author, in my opinion, is far too keen on a strict medical model and acceptance of DSM IV TR "disorders" and outlier conditions as diseases for which there is a pill lying in wait. The text glosses over these controversies the way that Powerpoint does at a pharma sponsored CME conference.

Nevertheless the chapter on antidepressant augmentation was excellent, though in practice I think it is foolish to use lithium for unipolar depression augmentation because it is the easiest drug to overdose on (and of course one of the big selling points of the SSRIs over TCAs to begin with was the safety factor in a suicide attempt.) One treatment that I was not aware of, and I will definitely start using in refractory cases, is MTHF supplementation which appears very safe and effective. I also learned quite a bit about alpha-2-delta ligands in the excellent chapter on ion channel blockers.

One chapter I had a lot of problems with was sleep disorders. In my opinion, the author is too cavalier about using benzo hypnotics, despite the fact that most evidence based treatment guidelines (i.e ACOEM) specifically warn against this except as a very short-term solution. I am disappointed that he failed to mention that these a history of alcohol or drug dependence changes the whole treatment paradigm. He seems enthusiastic about the "Z" hypnotics despite the scandalous promotion of Ambien as nonaddictive, a claim the manufacturer Aventis was forced to rescind. Not to mention the literature on sleepwalking and sleep driving with this drug (the Patrick Kennedy incident may have been related to this).

Stahl's Essential Psychopharmacology: Neuroscientific Basis and Practical Applications – Bargain Price, March 17, 2008 Download

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