Monday, September 9, 2013

The Maudsley Prescribing Guidelines in Psychiatry – April 2, 2012


The Maudsley Prescribing Guidelines in Psychiatry Paperback – April 2, 2012

Author: Visit Amazon's David Taylor Page | Language: English | ISBN: 0470979488 | Format: PDF, EPUB

The Maudsley Prescribing Guidelines in Psychiatry – April 2, 2012
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Review

“This comprehensive guide presents clinicians with evidence-based information on prescribing psychotropic drugs for mental health … This book will help nurses to be confident, sensitive and informed when discussing medication with patients and relatives, exploring treatment options within their professional teams and liaising with allied health professionals.”  (Nursing Standard, 30 May 2012)

From the Back Cover

This book is the essential guide for anyone responsible for prescribing, dispensing or
administering drugs for patients with mental health disorders. All the evidence has been
reviewed and summarised succinctly by an expert team of psychiatrists and pharmacists.

The evidence base for drug treatments in psychiatry ranges from meta-analyses and
randomised controlled clinical trials to single case reports, from NICE guidelines to
individual SPCs. Where to look for information when transferring a patient from one
drug to another or when dealing with a complex patient (for example, with co-morbid
epilepsy or liver disease or HIV infection)? The Maudsley Prescribing Guidelines are
established as the leading clinical relevant reference for handling complex prescribing
problems and for formulating prescribing policy.

This new edition makes greater use of tables and boxes to facilitate quick reference and
includes new sections on cytochrome-mediated interactions, psychiatric side effects of
non-psychotropic drugs and on GBL and GHB dependence.

Chapters cover plasma monitoring, schizophrenia, bipolar disorder, depression and
anxiety, children and adolescents, substance misuse and special patient groups. Each
section has a full reference list. The book covers prescribing drugs outside their licensed
indications and their interaction with substances such as alcohol, nicotine and caffeine.

Trainees will gain important information regarding the rational, safe and effective use
of medications for patients with mental illness. Experienced clinicians will find excellent
guidance regarding more complex issues that they may not encounter regularly.

Praise for previous editions:
“I would regard this book as mandatory for any pharmacist directly involved in the
care of patients with a psychiatric diagnosis, be they primary or secondary care-based.”
The Pharmaceutical Journal

“An excellent book and a ‘must’ for practising psychiatrists… not only will the rational
prescribing of psychotropic drugs drastically improve but, more importantly, the
patient will certainly benefit.”
Human Psychopharmacology

See all Editorial Reviews

Books with free ebook downloads available The Maudsley Prescribing Guidelines in Psychiatry – April 2, 2012
  • Paperback: 680 pages
  • Publisher: Wiley-Blackwell; 11 edition (April 2, 2012)
  • Language: English
  • ISBN-10: 0470979488
  • ISBN-13: 978-0470979488
  • Product Dimensions: 8.3 x 7.1 x 1.2 inches
  • Shipping Weight: 2.2 pounds (View shipping rates and policies)
  • Amazon Best Sellers Rank: #44,140 in Books (See Top 100 in Books)
    • #4 in Books > Medical Books > Pharmacology > Clinical
    • #15 in Books > Medical Books > Psychology > Psychopharmacology
    • #17 in Books > Health, Fitness & Dieting > Psychology & Counseling > Psychopharmacology
Preface ix


Acknowledgements x


Notes on using The Maudsley Prescribing Guidelines xi


Notes on inclusion of drugs xi


List of abbreviations xii

Chapter 1 Plasma level monitoring of psychotropic drugs and anticonvulsants 1


Interpreting sample results 2

Chapter 2 Schizophrenia 11


Antipsychotic drugs 11


Antipsychotic drugs: equivalent doses 13


Antipsychotic drugs: minimum effective doses 14


Antipsychotic drugs: licensed maximum doses 16


New antipsychotic drugs 17


Antipsychotic drugs: general principles of prescribing 21


National Institute for Health and Clinical Excellence guidelines for the treatment of schizophrenia 22


Treatment algorithms for schizophrenia 24


Antipsychotic drugs: monitoring of metabolic effects 26


Switching antipsychotic drugs because of poor tolerability 31


Antipsychotic response: to increase the dose, to switch, to add or just wait – what is the right move? 33


Speed and onset of antipsychotic drug action 36


First-generation antipsychotic drugs: place in therapy 39


Antipsychotic drugs: long-acting injections 40


Risperidone long-acting injection 44


Paliperidone palmitate long-acting injection 47


Management of patients on long-term depots: dose reduction 50


Combined antipsychotic drugs 51


High-dose antipsychotic drugs: prescribing and monitoring 54


Negative symptoms in schizophrenia 57


Antipsychotic prophylaxis 60


Refractory schizophrenia and clozapine 64


Clozapine augmentation 66


Refractory schizophrenia: alternatives to clozapine 69


Clozapine: management of common adverse effects 75


Clozapine: uncommon or unusual adverse effects 78


Clozapine: serious haematological and cardiovascular adverse effects 80


Clozapine, neutropenia and lithium 84


Clozapine and chemotherapy 88


Clozapine-related hypersalivation 89


Guidelines for the initiation of clozapine for patients based in the community 92


Omega-3 fatty acids (fish oils) in schizophrenia 96


Extrapyramidal side-effects of antipsychotic drug treatment 98


Treatment of antipsychotic-induced akathisia 103


Treatment of tardive dyskinesia 105


Neuroleptic malignant syndrome 110


Catatonia 113


Cardiovascular effects of antipsychotic drug treatment 115


Antipsychotic drugs and hypertension 122


Hyperprolactinaemia 123


Antipsychotic-induced weight gain 126


Treatment of drug-induced weight gain 128


Antipsychotic drugs, diabetes and impaired glucose tolerance 132


Antipsychotic drugs and dyslipidaemia 138


Antipsychotic drugs and sexual dysfunction 142


Antipsychotic-associated hyponatraemia 148


Antipsychotics and pneumonia 150


Relative adverse effects of antipsychotic drugs: a rough guide 151

Chapter 3 Bipolar disorder 153


Valproate 153


Lithium 159


Carbamazepine 168


Physical monitoring of people with bipolar disorder 173


Treatment of acute mania or hypomania 176


Antipsychotic drugs in bipolar disorder 182


Bipolar depression 185


Rapid cycling bipolar disorder 191


Prophylaxis in bipolar disorder 193

Chapter 4 Depression and anxiety 197


Depression 197


Antidepressants 201


Treatment of resistant depression 222


Treatment of psychotic depression 233


Electroconvulsive therapy and psychotropic drugs 235


Psychostimulants in depression 239


Treatment of depression in the elderly 243


Treatment of depression in stroke 247


Adverse effects of antidepressants 249


Selective serotonin reuptake inhibitors and bleeding 252


Depression and diabetes 255


Cardiac effects of antidepressants 257


Antidepressants and sexual dysfunction 264


Antidepressants and hyperprolactinaemia 268


Antidepressants: swapping and stopping 270


St John’s wort in the treatment of depression 278


Drug interactions with antidepressants 281


Alternative routes of administration for antidepressants 286


Anxiety spectrum disorders 292


Benzodiazepines in the treatment of psychiatric disorders 301


Benzodiazepines and disinhibition 304


Benzodiazepines: dependence and detoxification 306


Insomnia 310

Chapter 5 Children and adolescents 315


Principles of prescribing practice in childhood and adolescence 315


Depression in children and adolescents 316


Bipolar illness in children and adolescents 321


Psychosis in children and adolescents 326


Anxiety in children and adolescents 327


Obsessive compulsive disorder in children and adolescents 328


Attention deficit hyperactivity disorder 332


Autism spectrum disorders 337


Tics and Tourette’s syndrome 345


Melatonin in the treatment of insomnia in children and adolescents 349


Rapid tranquillisation in children and adolescents 351


Doses of commonly used psychotropic drugs in children and adolescents 354

Chapter 6 Substance misuse 355


Alcohol dependence 356


Opioid misuse and dependence 372


Nicotine and smoking cessation 398


Stimulant drugs of dependence 406


Benzodiazepine misuse 407


-Butaryl-lactone and -hydroxybutyrate dependence 408


Drugs of misuse: a summary 410


Interactions between ‘street drugs’ and prescribed psychotropic drugs 414

Chapter 7 Use of psychotropic drugs in special patient groups 419


Epilepsy 419


Pregnancy 430


Breast feeding 446


Renal impairment 462


Hepatic impairment 478


Prescribing in the elderly 487


Dementia 490


Behavioural and psychological symptoms of dementia 509


Parkinson’s disease 518


Multiple sclerosis 522


Eating disorders 527


Acutely disturbed or violent behaviour 531


Psychotropic medications for adults with learning disabilities 539


Borderline personality disorder 545


Delirium 547


Huntington’s disease 554


Psychotropic drugs and surgery 558


Prescribing psychotropic drugs for patients with HIV infection 564


Psychotropic drugs and cytochrome (CYP) function 573


Summary of psychiatric side-effects of non-psychotropic drugs 578

Chapter 8 Miscellaneous conditions and substances 587


Psychotropic drugs in overdose 587


Biochemical and haematological effects of psychotropic drugs 593


Prescribing drugs outside their licensed indications 604


Observations on the placebo effect in mental illness 606


Drug interactions with alcohol 608


Nicotine 613


Smoking and psychotropic drugs 616


Caffeine 618


Complementary therapies 624


Enhancing medication adherence 628


Driving and psychotropic medicines 634


Covert administration of medicines within food and drink 643


Index 647

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